Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.38 |
| ▸ | HTR2A | P28223 | 8/20 | 0.38 |
| ▸ | HTR2B | P41595 | 7/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767050 | 1.00 | HTR2C (0.38) | HTR2CHTR2AHTR2BCNR2LRRK2 | |
| SCHEMBL14765795 | 0.93 | HTR2C (0.41) | HTR2CHTR2AHTR2BHCRTR2PDE4D | |
| SCHEMBL14765975 | 0.91 | KDM1A (0.35) | HTR2CHTR2AHTR2BHCRTR2PDE4D | |
| SCHEMBL14765777 | 0.90 | PDE4D (0.35) | HTR2CHTR2BHCRTR2PDE4D | |
| SCHEMBL14766031 | 0.90 | LRRK2 (0.33) | HTR2CHTR2AHTR2BCNR2LRRK2 | |
| SCHEMBL14766939 | 0.90 | LRRK2 (0.33) | HTR2CHTR2AHTR2BCNR2LRRK2 | |
| SCHEMBL14767004 | 0.89 | FFAR1 (0.36) | HTR2CHTR2BPDE4D | |
| SCHEMBL14767048 | 0.89 | FFAR1 (0.38) | HTR2CHTR2B | |
| SCHEMBL12740630 | 0.88 | SCN9A (0.41) | HTR2CHTR2AHTR2BALOX5APFEN1 | |
| SCHEMBL12735806 | 0.88 | SCN9A (0.41) | HTR2CHTR2AHTR2BALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |