Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 10/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 7/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766001 | 0.93 | KDM1A (0.39) | KDM1AHTR2CHTR2BPDE4APDE4B | |
| SCHEMBL14765898 | 0.92 | KDM1A (0.34) | KDM1AHTR2CHTR2BHTR2AFPR2 | |
| SCHEMBL14765836 | 0.91 | HTR2C (0.38) | HTR2CHTR2BPDE4DHTR2AHCRTR2 | |
| SCHEMBL14767050 | 0.91 | HTR2C (0.38) | HTR2CHTR2BPDE4DHTR2AHCRTR2 | |
| SCHEMBL12735872 | 0.90 | SCN9A (0.39) | KDM1AHTR2CHTR2BPDE4APDE4B | |
| SCHEMBL14766039 | 0.90 | KDM1A (0.44) | KDM1AHTR2CHTR2BHTR2AHCRTR2 | |
| SCHEMBL14767048 | 0.89 | FFAR1 (0.38) | HTR2CHTR2B | |
| SCHEMBL14767004 | 0.89 | FFAR1 (0.36) | HTR2CHTR2BPDE4D | |
| SCHEMBL14765886 | 0.87 | KDM1A (0.33) | KDM1AHTR2CHTR2BPDE4APDE4B | |
| SCHEMBL14766440 | 0.87 | NAAA (0.35) | KDM1AHTR2CHTR2BPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |