Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 10/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766031 | 1.00 | LRRK2 (0.33) | LRRK2ALOX5APFEN1HTR2AHTR2C | |
| SCHEMBL14765673 | 0.93 | GABRA1 (0.33) | HTR2CHTR2BACACBSCN9AHCRTR2 | |
| SCHEMBL14765964 | 0.93 | SCN9A (0.33) | ALOX5APFEN1ACACBCNR2CNR1 | |
| SCHEMBL14766808 | 0.93 | SCN9A (0.33) | ALOX5APFEN1ACACBCNR2CNR1 | |
| SCHEMBL14765898 | 0.91 | KDM1A (0.34) | LRRK2HTR2AHTR2CHTR2BACACB | |
| SCHEMBL14766432 | 0.91 | FFAR1 (0.33) | LRRK2ACACBSCN9A | |
| SCHEMBL14767211 | 0.90 | FFAR1 (0.35) | ACACBSCN9A | |
| SCHEMBL12740631 | 0.90 | SCN9A (0.40) | ALOX5APFEN1HTR2AHTR2CHTR2B | |
| SCHEMBL14765836 | 0.90 | HTR2C (0.38) | LRRK2ALOX5APFEN1HTR2AHTR2C | |
| SCHEMBL12735802 | 0.90 | SCN9A (0.40) | ALOX5APFEN1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |