Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766301 | 0.94 | SCN9A (0.33) | KDM1ASCN9AFFAR4ACACB | |
| SCHEMBL14765683 | 0.93 | KDM1A (0.39) | KDM1ASCN9A | |
| SCHEMBL12735875 | 0.92 | SCN9A (0.39) | KDM1ASCN9AFFAR4FPR2HTR2A | |
| SCHEMBL14765975 | 0.92 | KDM1A (0.35) | KDM1ASCN9AFPR2HTR2AHTR2C | |
| SCHEMBL14766939 | 0.91 | LRRK2 (0.33) | SCN9ALRRK2ACACBHTR2AHTR2C | |
| SCHEMBL14766031 | 0.91 | LRRK2 (0.33) | SCN9ALRRK2ACACBHTR2AHTR2C | |
| SCHEMBL14765793 | 0.91 | KDM1A (0.32) | KDM1ASCN9AFFAR4 | |
| SCHEMBL14767211 | 0.90 | FFAR1 (0.35) | SCN9AFFAR4ACACB | |
| SCHEMBL14766039 | 0.89 | KDM1A (0.44) | KDM1ASCN9ALRRK2FPR2GPR119 | |
| SCHEMBL14766708 | 0.89 | FFAR1 (0.38) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |