Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765850 | 0.98 | HDAC8 (0.33) | S1PR1S1PR3AHRHDAC8 | |
| SCHEMBL14766123 | 0.94 | — | — | |
| SCHEMBL14766211 | 0.94 | S1PR1 (0.35) | S1PR1S1PR3AHRHDAC8 | |
| SCHEMBL14766685 | 0.94 | AHR (0.31) | AHRHDAC8 | |
| SCHEMBL14765922 | 0.92 | S1PR1 (0.34) | S1PR1S1PR3AHRHDAC8 | |
| SCHEMBL14766213 | 0.92 | HMOX1 (0.35) | S1PR1S1PR3AHRHDAC8 | |
| SCHEMBL14766379 | 0.91 | HDAC8 (0.33) | AHRHDAC8 | |
| SCHEMBL14765901 | 0.89 | GABRA1 (0.30) | — | |
| SCHEMBL14766883 | 0.89 | GABRA1 (0.30) | — | |
| SCHEMBL12734550 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |