Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766682 | 0.94 | AHR (0.42) | AHRHDAC8S1PR1S1PR3FFAR1 | |
| SCHEMBL14765718 | 0.93 | AHR (0.46) | AHRHDAC8S1PR1S1PR3FFAR1 | |
| SCHEMBL14765914 | 0.92 | FFAR1 (0.39) | AHRFFAR1FFAR4PTGS1PTGS2 | |
| SCHEMBL12734805 | 0.92 | NFE2L2 (0.38) | HDAC8S1PR1S1PR3FFAR1FFAR4 | |
| SCHEMBL14765711 | 0.92 | FFAR1 (0.44) | AHRHDAC8S1PR1S1PR3FFAR1 | |
| SCHEMBL14765925 | 0.91 | AHR (0.44) | AHRHDAC8S1PR1S1PR3FFAR1 | |
| SCHEMBL14765972 | 0.90 | AHR (0.39) | AHRHDAC8PTGS1PTGS2ABCG2 | |
| SCHEMBL14766665 | 0.90 | AHR (0.39) | AHRHDAC8PTGS1PTGS2ABCG2 | |
| SCHEMBL14766592 | 0.90 | AHR (0.42) | AHRHDAC8S1PR1S1PR3FFAR1 | |
| SCHEMBL10301741 | 0.89 | HMOX1 (0.35) | AHRHDAC8S1PR1S1PR3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |