SCHEMBL14765976

SCHEMBL14765976

CCCCOc1ccc(-c2ccc(CCc3ccc(-c4ccc(OCC)c(F)c4F)cc3)c(F)c2F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SLCO1B3 Q9NPD5 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
CYP2D6 P10635 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
S1PR1 P21453 3/20 0.38
S1PR3 Q99500 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767070 1.00 CYP3A4 (0.39) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL14766518 0.96 CYP3A4 (0.40) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL14766029 0.96 CYP3A4 (0.40) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL21869910 0.95 CNR2 (0.39) SMN1; SMN2L3MBTL1MAPTRAB9ACYP2D6
SCHEMBL14766907 0.94 LMNA (0.39) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL14766054 0.94 LMNA (0.39) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL14766925 0.93 FFAR4 (0.41) ALDH1A1LMNAL3MBTL1MAPTRAB9A
SCHEMBL14766365 0.93 FFAR4 (0.41) ALDH1A1LMNAL3MBTL1MAPTRAB9A
SCHEMBL14766002 0.91 S1PR1 (0.44) CYP3A4MEN1USP2ALDH1A1LMNA
SCHEMBL10301921 0.90 RARB (0.39) MEN1USP2ALDH1A1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed