Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766365 | 1.00 | FFAR4 (0.41) | FFAR4FFAR1NQO1L3MBTL1MAPT | |
| SCHEMBL1243473 | 0.95 | FFAR4 (0.40) | FFAR4FFAR1CTSLCTSSCTSK | |
| SCHEMBL14767070 | 0.93 | CYP3A4 (0.39) | FFAR4FFAR1L3MBTL1MAPTRAB9A | |
| SCHEMBL14765976 | 0.93 | CYP3A4 (0.39) | FFAR4FFAR1L3MBTL1MAPTRAB9A | |
| SCHEMBL12718657 | 0.92 | CALM1 (0.42) | FFAR4FFAR1MAPTCALM1KDM4E | |
| SCHEMBL12821268 | 0.92 | CALM1 (0.42) | FFAR4FFAR1MAPTCALM1KDM4E | |
| SCHEMBL12717240 | 0.91 | FFAR4 (0.39) | FFAR4FFAR1CTSLCTSSCTSK | |
| SCHEMBL12740090 | 0.91 | FFAR4 (0.39) | FFAR4FFAR1CTSLCTSSCTSK | |
| SCHEMBL10301920 | 0.91 | CTSL (0.44) | FFAR4FFAR1CTSLCTSSCTSK | |
| SCHEMBL12740092 | 0.91 | CTSL (0.41) | FFAR4FFAR1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |