SCHEMBL14765983

SCHEMBL14765983

CCOc1ccc(-c2ccc(COc3ccc(-c4ccc(OCC)c(F)c4)cc3)c(F)c2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.47
PPARD Q03181 6/20 0.47
NAAA Q02083 1/20 0.44
CACNA1C Q13936 1/20 0.41
FFAR4 Q5NUL3 2/20 0.38
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
GYS1 P13807 2/20 0.36
FAAH O00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12823271 0.94 FFAR1 (0.43) FFAR1PPARDNAAACACNA1CGYS1
SCHEMBL12737090 0.94 FFAR1 (0.42) FFAR1PPARDNAAACACNA1CFFAR4
SCHEMBL14765924 0.93 RARB (0.42) FFAR1PPARDNAAACACNA1CFFAR4
SCHEMBL12737080 0.93 FFAR1 (0.44) FFAR1PPARDNAAACACNA1CFFAR4
SCHEMBL12737089 0.92 FFAR1 (0.45) FFAR1PPARDNAAACACNA1CFFAR4
SCHEMBL12737082 0.91 FFAR1 (0.42) FFAR1PPARDNAAACACNA1CFFAR4
SCHEMBL14766202 0.90 FFAR1 (0.42) FFAR1PPARDNAAACACNA1CFFAR4
SCHEMBL12737085 0.90 FFAR1 (0.40) FFAR1PPARDNAAACACNA1CPPARG
SCHEMBL14766253 0.90 FFAR1 (0.41) FFAR1PPARDNAAACACNA1CFFAR4
SCHEMBL14767163 0.90 FFAR1 (0.41) FFAR1PPARDNAAACACNA1CFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed