SCHEMBL12823271

SCHEMBL12823271

CCOc1ccc(-c2ccc(OCc3ccc(-c4ccc(OC)cc4)c(F)c3F)cc2)cc1F

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.43
PPARD Q03181 4/20 0.43
NAAA Q02083 1/20 0.42
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GYS1 P13807 4/20 0.40
LMNA P02545 2/20 0.38
HTT P42858 1/20 0.38
SYK P43405 2/20 0.37
CACNA1C Q13936 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
MAPT P10636 2/20 0.37
PTGER4 P35408 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765983 0.94 FFAR1 (0.47) FFAR1PPARDNAAAGYS1CACNA1C
SCHEMBL12823084 0.92 FFAR1 (0.43) FFAR1PPARDNAAAPOLBL3MBTL1
SCHEMBL12737090 0.91 FFAR1 (0.42) FFAR1PPARDNAAAGYS1CACNA1C
SCHEMBL13586554 0.91 LMNA (0.39) FFAR1POLBL3MBTL1GYS1LMNA
SCHEMBL12823203 0.91 LMNA (0.39) FFAR1POLBL3MBTL1GYS1LMNA
SCHEMBL12737080 0.90 FFAR1 (0.44) FFAR1PPARDNAAAGYS1CACNA1C
SCHEMBL14765924 0.90 RARB (0.42) FFAR1PPARDNAAAL3MBTL1GYS1
SCHEMBL10303274 0.89 FFAR1 (0.46) FFAR1PPARDNAAAPOLBL3MBTL1
SCHEMBL12737089 0.89 FFAR1 (0.45) FFAR1PPARDNAAAGYS1CACNA1C
SCHEMBL12737082 0.88 FFAR1 (0.42) FFAR1PPARDNAAACACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, LAS1L, EFHD2 FFAR1 247/4885PPARD 3762/4885NAAA 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.