Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766610 | 0.94 | MAPT (0.48) | MAPTTHRBTP53FFAR1KMT2A | |
| SCHEMBL14767114 | 0.91 | MAPT (0.47) | MAPTTHRBTP53FFAR1KMT2A | |
| SCHEMBL12823424 | 0.91 | KMT2A (0.50) | MAPTTHRBTP53FFAR1KMT2A | |
| SCHEMBL14766010 | 0.91 | MAPT (0.50) | MAPTTHRBTP53KMT2APOLB | |
| SCHEMBL12823467 | 0.91 | MAPT (0.50) | MAPTTHRBTP53KMT2APOLB | |
| SCHEMBL12718259 | 0.90 | RXRA (0.41) | MAPTTHRBTP53FFAR1KMT2A | |
| SCHEMBL14766300 | 0.90 | RARB (0.47) | MAPTTHRBTP53FFAR1KMT2A | |
| SCHEMBL12822923 | 0.89 | MAPT (0.49) | MAPTTHRBTP53FFAR1KMT2A | |
| SCHEMBL13586232 | 0.89 | MAPT (0.45) | MAPTTHRBTP53FFAR1KMT2A | |
| SCHEMBL12737525 | 0.89 | THRB (0.48) | MAPTTHRBTP53FFAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |