Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766352 | 0.96 | ELOVL1 (0.38) | ELOVL1S1PR1CNR2CNR1PTGES | |
| SCHEMBL14766722 | 0.91 | CNR2 (0.39) | ELOVL1S1PR1CNR2CNR1PTGES | |
| SCHEMBL12738835 | 0.88 | CYP11B1 (0.36) | S1PR1CNR2CNR1S1PR3CTSL | |
| SCHEMBL14766907 | 0.88 | LMNA (0.39) | S1PR1CNR2S1PR3CTSLCTSS | |
| SCHEMBL14766054 | 0.88 | LMNA (0.39) | S1PR1CNR2S1PR3CTSLCTSS | |
| SCHEMBL14766434 | 0.88 | S1PR1 (0.45) | ELOVL1S1PR1CNR2CNR1PTGES | |
| SCHEMBL12738849 | 0.87 | CNR2 (0.35) | S1PR1CNR2CNR1S1PR3CTSL | |
| SCHEMBL14766725 | 0.87 | CNR2 (0.35) | S1PR1CNR2CNR1S1PR3CTSL | |
| SCHEMBL21869910 | 0.87 | CNR2 (0.39) | S1PR1CNR2CNR1S1PR3CTSL | |
| SCHEMBL14766518 | 0.86 | CYP3A4 (0.40) | S1PR1CNR2S1PR3CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |