Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766697 | 0.97 | TUBB1 (0.34) | TUBB1ALDH1A1SMN1; SMN2TDP1SCN9A | |
| SCHEMBL14767007 | 0.94 | TUBB1 (0.34) | TUBB1ALDH1A1SMN1; SMN2TDP1SCN9A | |
| SCHEMBL15495057 | 0.93 | TUBB1 (0.40) | TUBB1KDM1AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766515 | 0.92 | SCN9A (0.32) | TUBB1ALDH1A1SMN1; SMN2TDP1SCN9A | |
| SCHEMBL14766675 | 0.91 | SCN9A (0.33) | TUBB1ALDH1A1SMN1; SMN2TDP1SCN9A | |
| SCHEMBL14766691 | 0.91 | TUBB1 (0.41) | TUBB1KDM1AALDH1A1MEN1KMT2A | |
| SCHEMBL12739054 | 0.87 | SCN9A (0.35) | TUBB1ALDH1A1SMN1; SMN2TDP1SCN9A | |
| SCHEMBL13586161 | 0.87 | TUBB1 (0.44) | TUBB1KDM1AALDH1A1MEN1KMT2A | |
| SCHEMBL12739042 | 0.86 | TUBB1 (0.38) | TUBB1KDM1ATNFRSF1AHPGDTOP2A | |
| SCHEMBL14765808 | 0.86 | KDM1A (0.37) | KDM1ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |