SCHEMBL14766675

SCHEMBL14766675

C=CCCOc1ccc(/C=C/C2CCC(c3ccc(C4CCC(OCCCC)CC4)c(F)c3F)CC2)cc1F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.33
TUBB1 Q9H4B7 1/20 0.31
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766515 0.97 SCN9A (0.32) SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14767161 0.94 TUBB1 (0.33) TUBB1ALDH1A1
SCHEMBL14766697 0.94 TUBB1 (0.34) SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14767007 0.91 TUBB1 (0.34) SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14766307 0.91 TUBB1 (0.38) SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14765831 0.88 SCN9A (0.31) SCN9A
SCHEMBL14766684 0.87 GABRA1 (0.32) SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1
SCHEMBL14766869 0.87 SCN9A (0.31) SCN9A
SCHEMBL14765902 0.87 SCN9A (0.31) SCN9A
SCHEMBL14766612 0.87 SCN9A (0.31) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed