Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766675 | 0.97 | SCN9A (0.33) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766697 | 0.95 | TUBB1 (0.34) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14767007 | 0.92 | TUBB1 (0.34) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14766307 | 0.92 | TUBB1 (0.38) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14767161 | 0.91 | TUBB1 (0.33) | TUBB1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL12739071 | 0.88 | KDM4E (0.33) | TUBB1ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL14766371 | 0.88 | MEN1 (0.33) | — | |
| SCHEMBL14766426 | 0.87 | GABRA1 (0.33) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL15495057 | 0.87 | TUBB1 (0.40) | SCN9ATUBB1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14765796 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |