SCHEMBL14766334

SCHEMBL14766334

CCOc1ccc(/C=C/c2ccc(-c3ccc(C4CCC(OCC)CC4)c(F)c3F)cc2)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.32
FGFR2 P21802 1/20 0.32
FPR2 P25090 2/20 0.31
TUBB1 Q9H4B7 1/20 0.31
ACACB O00763 1/20 0.30
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765704 1.00 FGFR1 (0.32) FGFR1FGFR2FPR2TUBB1ACACB
SCHEMBL14767032 0.92 HTR2C (0.31)
SCHEMBL14765821 0.92 HTR2C (0.31)
SCHEMBL12822935 0.92 ALOX5AP (0.33) FGFR1FGFR2FPR2TUBB1ALOX5AP
SCHEMBL13586495 0.92 ALOX5AP (0.33) FGFR1FGFR2FPR2TUBB1ALOX5AP
SCHEMBL14767055 0.92
SCHEMBL14765820 0.92
SCHEMBL12739357 0.91 FPR2 (0.32) FGFR1FGFR2FPR2TUBB1ALOX5AP
SCHEMBL12734384 0.91 FPR2 (0.32) FGFR1FGFR2FPR2TUBB1ALOX5AP
SCHEMBL14767177 0.91 GABRA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed