Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476645 | 1.00 | PPARA (0.45) | PPARAPPARDMAPTL3MBTL1TDP1 | |
| SCHEMBL1047361 | 0.89 | MAPT (0.51) | MAPTL3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL6748734 | 0.89 | MAPT (0.51) | MAPTL3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL1044851 | 0.88 | MAPT (0.53) | MAPTL3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL31542557 | 0.85 | NR5A1 (0.56) | PPARAPPARDMAPTNPC1RAB9A | |
| SCHEMBL1047649 | 0.82 | DRD2 (0.52) | MAPTL3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL16798419 | 0.81 | HRH3 (0.49) | PPARAPPARDMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL13238254 | 0.81 | RARB (0.54) | MAPTL3MBTL1NPC1RAB9AHSD17B10 | |
| SCHEMBL28684064 | 0.80 | LMNA (0.48) | PPARAMAPTNPC1RAB9AHSD17B10 | |
| SCHEMBL14984020 | 0.80 | MAPT (0.60) | MAPTL3MBTL1TDP1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7914485-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100016941-A1 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-7582078-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| EP-2068959-A2 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | Boston Scientific Limited (BB) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008045166-A2 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC LIMITED (BB) | 2008-04-17 | — | — | WO | disclosed |
| US-20070191814-A1 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2007-08-16 | — | — | US | disclosed |