Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.34 |
| ▸ | HTR2B | P41595 | 6/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 7/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767161 | 0.91 | TUBB1 (0.33) | TUBB1HPGD | |
| SCHEMBL14766691 | 0.91 | TUBB1 (0.41) | TUBB1HPGD | |
| SCHEMBL12739065 | 0.89 | HTR2C (0.36) | HTR2CHTR2BTUBB1HTR2AADRB2 | |
| SCHEMBL12739046 | 0.87 | TUBB1 (0.41) | TUBB1HPGD | |
| SCHEMBL14766515 | 0.86 | SCN9A (0.32) | TUBB1PDE4BHPGD | |
| SCHEMBL10301906 | 0.86 | HTR2C (0.35) | HTR2CHTR2BTUBB1HTR2AADRB2 | |
| SCHEMBL14766230 | 0.86 | HTR2C (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL14766378 | 0.86 | TUBB1 (0.34) | HTR2CHTR2BTUBB1HTR2AADRB2 | |
| SCHEMBL14766675 | 0.86 | SCN9A (0.33) | TUBB1 | |
| SCHEMBL14766697 | 0.85 | TUBB1 (0.34) | TUBB1PDE4BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |