SCHEMBL14766550

SCHEMBL14766550

CCOc1ccc(COc2ccc(-c3ccc(C4CCC(OCC)CC4)c(F)c3F)cc2)cc1F

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 8/20 0.41
FFAR1 O14842 8/20 0.41
PPARA Q07869 3/20 0.39
PPARG P37231 1/20 0.39
NAAA Q02083 2/20 0.38
FFAR4 Q5NUL3 1/20 0.37
GYS1 P13807 6/20 0.37
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767016 0.94 FFAR1 (0.41) PPARDFFAR1PPARANAAA
SCHEMBL14766979 0.94 FFAR1 (0.41) PPARDFFAR1PPARAPPARGNAAA
SCHEMBL14766567 0.93 PPARD (0.39) PPARDFFAR1PPARAPPARGNAAA
SCHEMBL14766873 0.92 PPARD (0.41) PPARDFFAR1PPARAPPARGFFAR4
SCHEMBL14767003 0.92 PPARD (0.38) PPARDFFAR1PPARAPPARGNAAA
SCHEMBL12740422 0.91 PPARD (0.42) PPARDFFAR1PPARAPPARGFFAR4
SCHEMBL14766702 0.91 GYS1 (0.41) PPARDFFAR1PPARAPPARGNAAA
SCHEMBL14766598 0.91 PPARD (0.37) PPARDFFAR1PPARAPPARGNAAA
SCHEMBL14766989 0.91 NAAA (0.37) PPARDFFAR1PPARAPPARGNAAA
SCHEMBL12718834 0.90 NAAA (0.42) PPARDFFAR1PPARAPPARGNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed