SCHEMBL14766710

SCHEMBL14766710

C=CCCCOc1ccc(CCC2CCC(c3ccc(-c4ccc(OCCCC)cc4)c(F)c3F)CC2)cc1F

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.35
S1PR1 P21453 4/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CNR1 P21554 1/20 0.33
FFAR4 Q5NUL3 3/20 0.33
S1PR3 Q99500 2/20 0.32
FAAH O00519 1/20 0.31
RARA P10276 1/20 0.31
RARB P10826 1/20 0.31
PPARD Q03181 2/20 0.31
FFAR1 O14842 1/20 0.31
ALOX5 P09917 2/20 0.31
PTGES O14684 1/20 0.31
PPARA Q07869 1/20 0.30
KCNH2 Q12809 1/20 0.30
GLA P06280 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767026 0.97 CNR2 (0.35) CNR2S1PR1GABRA1GABRB2CNR1
SCHEMBL14766425 0.93 S1PR1 (0.37) S1PR1FFAR4S1PR3FAAHRARA
SCHEMBL14766827 0.93 GABRA1 (0.32) GABRA1GABRB2FFAR4PPARDFFAR1
SCHEMBL14766500 0.92 FFAR4 (0.35) S1PR1FFAR4S1PR3FAAHRARA
SCHEMBL14766851 0.92 S1PR1 (0.36) S1PR1FFAR4S1PR3FAAHRARA
SCHEMBL12739880 0.91 ALOX5AP (0.32) GABRA1GABRB2FFAR4
SCHEMBL14766852 0.89 GABRA1 (0.36) CNR2S1PR1GABRA1GABRB2CNR1
SCHEMBL12718918 0.88 GABRA1 (0.31) S1PR1GABRA1GABRB2
SCHEMBL14765769 0.88 CNR2 (0.32) CNR2GABRA1GABRB2CNR1FFAR4
SCHEMBL14766394 0.88 CNR2 (0.32) CNR2GABRA1GABRB2CNR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed