Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GYS1 | P13807 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766954 | 0.97 | GABRA1 (0.35) | GABRA1GABRB2CNR2NAAARARA | |
| SCHEMBL14766790 | 0.95 | GABRA1 (0.35) | GABRA1GABRB2CNR2NAAACNR1 | |
| SCHEMBL14766846 | 0.94 | NAAA (0.38) | NAAARARARARBFFAR4PPARD | |
| SCHEMBL14766837 | 0.93 | GABRA1 (0.35) | GABRA1GABRB2CNR2NAAACNR1 | |
| SCHEMBL14766829 | 0.92 | FFAR1 (0.36) | GABRA1GABRB2NAAAFFAR4PPARD | |
| SCHEMBL14766637 | 0.92 | FFAR1 (0.37) | GABRA1GABRB2NAAARARARARB | |
| SCHEMBL14766989 | 0.91 | NAAA (0.37) | NAAARARARARBFFAR4PPARD | |
| SCHEMBL14766882 | 0.91 | PPARD (0.36) | GABRA1GABRB2NAAAFFAR4PPARD | |
| SCHEMBL12740344 | 0.91 | SIGMAR1 (0.39) | GABRA1GABRB2NAAACNR1FFAR4 | |
| SCHEMBL14766992 | 0.90 | SCN9A (0.35) | GABRA1GABRB2CNR2NAAACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |