Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.34 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766722 | 0.90 | CNR2 (0.39) | GABRA1GABRB2ELOVL1PTGESCNR2 | |
| SCHEMBL12738860 | 0.89 | CYP11B1 (0.34) | GABRA1GABRB2ELOVL1CNR2FFAR4 | |
| SCHEMBL12738862 | 0.88 | CNR2 (0.31) | GABRA1GABRB2CNR2 | |
| SCHEMBL14766167 | 0.88 | CNR2 (0.36) | GABRA1GABRB2CNR2FFAR4CNR1 | |
| SCHEMBL14766597 | 0.88 | CNR2 (0.36) | GABRA1GABRB2CNR2FFAR4CNR1 | |
| SCHEMBL12822838 | 0.87 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL14766723 | 0.86 | CNR2 (0.39) | GABRA1GABRB2CNR2CNR1CTSL | |
| SCHEMBL12740118 | 0.86 | FFAR4 (0.35) | GABRA1GABRB2CNR2FFAR4CNR1 | |
| SCHEMBL12735599 | 0.86 | FFAR4 (0.35) | GABRA1GABRB2CNR2FFAR4CNR1 | |
| SCHEMBL12738863 | 0.85 | CYP11B1 (0.34) | GABRA1GABRB2ELOVL1CNR2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |