Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 11/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766956 | 0.97 | GYS1 (0.38) | NAAAPPARDFFAR1GYS1GABRA1 | |
| SCHEMBL14765802 | 0.94 | GYS1 (0.35) | NAAAPPARDFFAR1GYS1GABRA1 | |
| SCHEMBL14767035 | 0.92 | GABRA1 (0.34) | NAAAPPARDFFAR1GABRA1GABRB2 | |
| SCHEMBL14766702 | 0.91 | GYS1 (0.41) | NAAAPPARDFFAR1GYS1GABRA1 | |
| SCHEMBL14767065 | 0.91 | FFAR1 (0.41) | NAAAPPARDFFAR1CCR5HTR1A | |
| SCHEMBL14766718 | 0.91 | PPARD (0.36) | NAAAPPARDFFAR1GABRA1GABRB2 | |
| SCHEMBL12740917 | 0.90 | GYS1 (0.36) | PPARDFFAR1GYS1BCHEHTR6 | |
| SCHEMBL14767171 | 0.90 | GABRA1 (0.35) | NAAAGYS1GABRA1GABRB2HTR6 | |
| SCHEMBL14766075 | 0.90 | GABRA1 (0.35) | NAAAGYS1GABRA1GABRB2HTR6 | |
| SCHEMBL14767016 | 0.89 | FFAR1 (0.41) | NAAAPPARDFFAR1F10PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |