Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766390 | 0.93 | HTR1A (0.34) | NAAAHTR1ACHRNB2CHRNA4HTR6 | |
| SCHEMBL12740275 | 0.93 | NAAA (0.38) | NAAAHTR1ACHRNB2CHRNA4HTR6 | |
| SCHEMBL12718656 | 0.93 | NAAA (0.38) | NAAAHTR1ACHRNB2CHRNA4HTR6 | |
| SCHEMBL12740270 | 0.92 | NAAA (0.37) | NAAAHTR1ACHRNB2CHRNA4HTR6 | |
| SCHEMBL14766940 | 0.91 | NAAA (0.37) | NAAAHTR1ACHRNB2CHRNA4HTR6 | |
| SCHEMBL12740271 | 0.90 | NAAA (0.36) | NAAAHTR1ACHRNB2CHRNA4HTR6 | |
| SCHEMBL12740277 | 0.90 | NAAA (0.36) | NAAAHTR1AHTR6MAOAMAOB | |
| SCHEMBL14767021 | 0.90 | NAAA (0.40) | NAAAFFAR1 | |
| SCHEMBL14767273 | 0.90 | FFAR4 (0.40) | NAAAHTR6MAOBKCNH2ACACA | |
| SCHEMBL12740272 | 0.89 | NAAA (0.36) | NAAAHTR1ACHRNB2CHRNA4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |