Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA7 | P43166 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844672 | 0.95 | ALDH1A1 (0.62) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL9473505 | 0.92 | TSHR (0.59) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL12307337 | 0.90 | MAPT (0.61) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL4913453 | 0.87 | MAPT (0.69) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL28510538 | 0.86 | CA1 (0.66) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL70217 | 0.86 | CA1 (0.66) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL87450 | 0.85 | CA1 (0.83) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL3945844 | 0.84 | MAPT (0.72) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL3945839 | 0.84 | MAPT (0.72) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL7746905 | 0.83 | CA1 (0.79) | MEN1KMT2ALMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2020155595-A1 | AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR | 清华大学 | 2020-08-06 | — | — | WO | disclosed |
| CN-103374124-A | Preparation method and application of polymer-loaded trialkyl organic sulfenyl tin | SHENZHEN YINGLIHUA BIOLOG TECHNOLOGY CO LTD | 2013-10-30 | — | — | CN | disclosed |
| EP-2426134-A2 | Method of modulating stress-activated protein kinase system | Intermune, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20080199808-A1 | OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION | FUJIFILM CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20080199808-A1 | OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION | FUJIFILM CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |