Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NOS3 | P29474 | 2/20 | 0.54 |
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
| ▸ | NOS2 | P35228 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147669 | 0.90 | MEN1 (0.67) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3080726 | 0.88 | MAPT (0.75) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3080728 | 0.88 | MAPT (0.75) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15218694 | 0.86 | MAPT (0.53) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9844672 | 0.85 | ALDH1A1 (0.62) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15218703 | 0.84 | MAPT (0.57) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15218697 | 0.84 | MAPT (0.57) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10817298 | 0.83 | RAB9A (0.69) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9473505 | 0.83 | TSHR (0.59) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10025042 | 0.82 | ESR1 (0.79) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-09-22 | — | — | US | disclosed |
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | DCLRE1B, NSUN2, MTX2 | MAPT 4777/4885RAB9A 4822/4885NPC1 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.