Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.34 |
| ▸ | HTR2B | P41595 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766671 | 0.91 | GABRA1 (0.32) | BACE1 | |
| SCHEMBL14766317 | 0.90 | KDM1A (0.37) | ALDH1A1HTR6 | |
| SCHEMBL12739734 | 0.89 | HTR2C (0.36) | HTR2CHTR2BALDH1A1CYP2D6HTR2A | |
| SCHEMBL14766403 | 0.88 | DRD4 (0.38) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL14765886 | 0.86 | KDM1A (0.33) | HTR2CHTR2BHTR2A | |
| SCHEMBL14766624 | 0.86 | GLA (0.32) | — | |
| SCHEMBL10302175 | 0.86 | HTR2C (0.35) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL14767031 | 0.86 | GABRA1 (0.35) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL14766891 | 0.86 | SCN9A (0.33) | — | |
| SCHEMBL12739715 | 0.85 | KDM1A (0.35) | ALDH1A1MEN1KMT2ACYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |