Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766891 | 0.94 | SCN9A (0.33) | GABRA1GABRB2 | |
| SCHEMBL14766904 | 0.91 | HTR2C (0.34) | BACE1 | |
| SCHEMBL14766624 | 0.91 | GLA (0.32) | GABRA1GABRB2HPGD | |
| SCHEMBL12739735 | 0.90 | KDM4E (0.35) | HPGD | |
| SCHEMBL14766317 | 0.89 | KDM1A (0.37) | — | |
| SCHEMBL14767246 | 0.88 | DRD4 (0.36) | GABRA1GABRB2 | |
| SCHEMBL10302176 | 0.88 | MAPT (0.33) | — | |
| SCHEMBL12739739 | 0.88 | KDM4E (0.37) | HPGD | |
| SCHEMBL14765724 | 0.87 | KDM1A (0.32) | HPGD | |
| SCHEMBL14766389 | 0.86 | GABRA1 (0.36) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |