SCHEMBL14766911

SCHEMBL14766911

CCCCOc1ccc(-c2ccc(C3CCC(CCc4ccc(OCC)c(F)c4F)CC3)c(F)c2F)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.35
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
FFAR1 O14842 1/20 0.31
CYP2D6 P10635 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CNR2 P34972 2/20 0.31
RET P07949 1/20 0.30
ESR1 P03372 1/20 0.30
CNR1 P21554 1/20 0.30
RAB9A P51151 1/20 0.30
FPR2 P25090 1/20 0.30
CYP3A4 P08684 1/20 0.30
CTSL P07711 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765881 1.00 FFAR4 (0.35) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL14766324 0.97 FFAR4 (0.35) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL14766259 0.97 FFAR4 (0.35) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL14766461 0.95 FFAR4 (0.34) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL14765874 0.95 FFAR4 (0.34) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL14766462 0.94 FFAR4 (0.35) FFAR4RETESR1RAB9AFPR2
SCHEMBL14765771 0.94 FFAR4 (0.35) FFAR4RETESR1RAB9AFPR2
SCHEMBL14766394 0.91 CNR2 (0.32) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL14765769 0.91 CNR2 (0.32) FFAR4CHRM2CHRM4CHRM5CHRM1
SCHEMBL15381673 0.91 CTSL (0.34) FFAR4CNR2CNR1FPR2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed