SCHEMBL14765771

SCHEMBL14765771

CCOc1ccc(-c2ccc(CCC3CCC(c4ccc(OCC)c(F)c4F)CC3)c(F)c2F)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.35
CACNA2D1 P54289 1/20 0.32
FPR2 P25090 2/20 0.32
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SENP8 Q96LD8 1/20 0.31
NLRP3 Q96P20 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
FGFR1 P11362 1/20 0.30
FGFR2 P21802 1/20 0.30
RET P07949 1/20 0.30
ESR1 P03372 1/20 0.30
SSTR5 P35346 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766462 1.00 FFAR4 (0.35) FFAR4CACNA2D1FPR2ALOX5APFEN1
SCHEMBL14766911 0.94 FFAR4 (0.35) FFAR4FPR2RAB9ARETESR1
SCHEMBL14765881 0.94 FFAR4 (0.35) FFAR4FPR2RAB9ARETESR1
SCHEMBL13586219 0.94 FPR2 (0.34) FFAR4FPR2ALOX5APFEN1KCNH2
SCHEMBL13586075 0.94 FPR2 (0.34) FFAR4FPR2ALOX5APFEN1KCNH2
SCHEMBL12735087 0.92 ALOX5AP (0.33) FFAR4FPR2ALOX5APFEN1FGFR1
SCHEMBL12739815 0.92 ALOX5AP (0.33) FFAR4FPR2ALOX5APFEN1FGFR1
SCHEMBL14766603 0.92 CTSL (0.32) FFAR4
SCHEMBL14765995 0.92 CTSL (0.32) FFAR4
SCHEMBL14766324 0.91 FFAR4 (0.35) FFAR4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed