Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 7/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766406 | 0.97 | CRBN (0.37) | CRBNCNR2CNR1NAAAHTR2A | |
| SCHEMBL14766174 | 0.94 | CRBN (0.35) | CRBNNPC1RAB9ACNR2CNR1 | |
| SCHEMBL14766940 | 0.94 | NAAA (0.37) | CRBNNPC1RAB9ACNR2CNR1 | |
| SCHEMBL12740279 | 0.93 | CRBN (0.36) | CRBNRAB9ACNR2CNR1NAAA | |
| SCHEMBL12740278 | 0.91 | CNR2 (0.37) | CRBNCNR2CNR1NAAAHTR2A | |
| SCHEMBL14765908 | 0.90 | CRBN (0.36) | CRBNCNR2CNR1HTR2AHTR1A | |
| SCHEMBL14766709 | 0.90 | FFAR4 (0.39) | CRBNNPC1RAB9ANAAAHTR2A | |
| SCHEMBL14766918 | 0.90 | CRBN (0.33) | CRBNCNR2CNR1NAAAHTR2A | |
| SCHEMBL14766679 | 0.90 | FFAR4 (0.37) | CRBNNAAAHTR2AFFAR1ACACB | |
| SCHEMBL12740282 | 0.90 | CNR2 (0.39) | CRBNCNR2CNR1HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |