SCHEMBL14766918

SCHEMBL14766918

C=CCCCOc1ccc(COC2CCC(c3ccc(C4CCC(OCCCC)CC4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33
SLC10A2 Q12908 1/20 0.33
FFAR1 O14842 1/20 0.33
HTR2A P28223 2/20 0.32
CNR2 P34972 6/20 0.32
CNR1 P21554 3/20 0.32
NAAA Q02083 3/20 0.32
HTR6 P50406 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTR1A P08908 1/20 0.30
SCN9A Q15858 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766668 0.97 CRBN (0.33) CRBNSLC10A2FFAR1HTR2ACNR2
SCHEMBL14766269 0.94 SLC10A2 (0.33) CRBNSLC10A2FFAR1CNR2CNR1
SCHEMBL14766406 0.93 CRBN (0.37) CRBNFFAR1HTR2ACNR2CNR1
SCHEMBL14766732 0.92 FFAR4 (0.34) CRBNSLC10A2FFAR1HTR2ANAAA
SCHEMBL14766146 0.92 CRBN (0.32) CRBNSLC10A2CNR2CNR1SCN9A
SCHEMBL14767169 0.91 FFAR4 (0.36) SLC10A2FFAR1HTR2ANAAA
SCHEMBL12740287 0.91 HTR6 (0.32) NAAAHTR6ALDH1A1L3MBTL1HTR1A
SCHEMBL14766941 0.90 NAAA (0.33) NAAAHTR6HTR1A
SCHEMBL14766940 0.90 NAAA (0.37) CRBNFFAR1HTR2ACNR2CNR1
SCHEMBL14766916 0.90 CRBN (0.36) CRBNFFAR1HTR2ACNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed