Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766094 | 1.00 | FFAR1 (0.38) | FFAR1FFAR4KMT2AKDM4EMAPT | |
| SCHEMBL14767304 | 0.94 | RARB (0.39) | FFAR1FFAR4KMT2AKDM4EMAPT | |
| SCHEMBL14766333 | 0.94 | RARB (0.39) | FFAR1FFAR4KMT2AKDM4EMAPT | |
| SCHEMBL14766565 | 0.93 | FFAR1 (0.40) | FFAR1FFAR4KMT2AMAPTTHRB | |
| SCHEMBL12738144 | 0.92 | KDM4E (0.36) | FFAR1FFAR4KMT2AKDM4EMAPT | |
| SCHEMBL12741804 | 0.92 | KDM4E (0.36) | FFAR1FFAR4KMT2AKDM4EMAPT | |
| SCHEMBL14766245 | 0.91 | ALDH1A1 (0.41) | FFAR1FFAR4KMT2AMAPTL3MBTL1 | |
| SCHEMBL14767251 | 0.91 | ALDH1A1 (0.41) | FFAR1FFAR4KMT2AMAPTL3MBTL1 | |
| SCHEMBL14766236 | 0.90 | MAPT (0.41) | FFAR1FFAR4KMT2AKDM4EMAPT | |
| SCHEMBL14767077 | 0.90 | MAPT (0.41) | FFAR1FFAR4KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |