Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766333 | 1.00 | RARB (0.39) | RARBRARAALDH1A1L3MBTL1LMNA | |
| SCHEMBL14767251 | 0.97 | ALDH1A1 (0.41) | RARBRARAALDH1A1L3MBTL1LMNA | |
| SCHEMBL14766245 | 0.97 | ALDH1A1 (0.41) | RARBRARAALDH1A1L3MBTL1LMNA | |
| SCHEMBL14766094 | 0.94 | FFAR1 (0.38) | ALDH1A1L3MBTL1LMNAFFAR1FFAR4 | |
| SCHEMBL14767006 | 0.94 | FFAR1 (0.38) | ALDH1A1L3MBTL1LMNAFFAR1FFAR4 | |
| SCHEMBL14766670 | 0.92 | RARB (0.44) | RARBRARALMNANPC1CYP1A2 | |
| SCHEMBL14766713 | 0.92 | RARB (0.44) | RARBRARALMNANPC1CYP1A2 | |
| SCHEMBL14766393 | 0.92 | RARB (0.46) | RARBRARALMNANPC1CYP1A2 | |
| SCHEMBL12738144 | 0.90 | KDM4E (0.36) | ALDH1A1L3MBTL1LMNACYP1A2CYP2C19 | |
| SCHEMBL12741804 | 0.90 | KDM4E (0.36) | ALDH1A1L3MBTL1LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |