Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767083 | 0.96 | PRSS1 (0.41) | ALDH1A1L3MBTL1PRSS1ACRLMNA | |
| SCHEMBL14767300 | 0.94 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1PRSS1ACRLMNA | |
| SCHEMBL14767277 | 0.92 | PRSS1 (0.46) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL14767128 | 0.91 | KMT2A (0.41) | ALDH1A1L3MBTL1LMNANPC1THRB | |
| SCHEMBL12741928 | 0.91 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1PRSS1ACRNPC1 | |
| SCHEMBL14766452 | 0.91 | RARB (0.42) | ALDH1A1L3MBTL1PRSS1ACRLMNA | |
| SCHEMBL14767168 | 0.91 | MAPT (0.42) | ALDH1A1L3MBTL1PRSS1ACRLMNA | |
| SCHEMBL14766751 | 0.90 | FFAR1 (0.46) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL14767080 | 0.90 | MAPT (0.45) | L3MBTL1PRSS1ACRLMNANPC1 | |
| SCHEMBL14767234 | 0.90 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1PRSS1ACRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |