Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767240 | 0.94 | KMT2A (0.41) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL14767083 | 0.93 | PRSS1 (0.41) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL14767126 | 0.91 | ALDH1A1 (0.44) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL12741921 | 0.91 | ALDH1A1 (0.38) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL14766216 | 0.91 | MAPT (0.42) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL14767086 | 0.90 | MAPT (0.43) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL14767151 | 0.89 | KMT2A (0.45) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL14767262 | 0.89 | FFAR1 (0.44) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL12741928 | 0.89 | ALDH1A1 (0.40) | KMT2AFFAR1FFAR4MAPTTHRB | |
| SCHEMBL14766478 | 0.88 | MAPT (0.42) | KMT2AFFAR1FFAR4MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |