Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767229 | 0.98 | FFAR1 (0.38) | RARARARBFAAHSCN9AFFAR4 | |
| SCHEMBL14767291 | 0.96 | FFAR1 (0.39) | RARARARBFAAHSCN9AFFAR4 | |
| SCHEMBL12742366 | 0.95 | SCN9A (0.37) | RARARARBFAAHSCN9AFFAR4 | |
| SCHEMBL14767267 | 0.94 | FAAH (0.41) | RARARARBFAAHSCN9AFFAR4 | |
| SCHEMBL14767293 | 0.93 | FFAR4 (0.35) | RARARARBFAAHSCN9AFFAR4 | |
| SCHEMBL14767130 | 0.93 | SCN9A (0.36) | RARARARBFAAHSCN9AFFAR4 | |
| SCHEMBL12742371 | 0.93 | SCN9A (0.36) | RARBSCN9AFFAR4FFAR1PPARD | |
| SCHEMBL12742379 | 0.92 | THRA (0.36) | SCN9AFFAR4FFAR1PPARDPTPN11 | |
| SCHEMBL12742374 | 0.92 | THRA (0.36) | SCN9AFFAR4FFAR1PPARDPTPN11 | |
| SCHEMBL12742375 | 0.92 | THRA (0.36) | SCN9AFFAR4FFAR1PPARDPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |