SCHEMBL14767192

SCHEMBL14767192

CCCCOC1CCC(c2ccc(C3CCC(C(=O)Oc4ccc(OCC)cc4F)CC3)c(F)c2F)CC1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 6/20 0.38
FAAH O00519 3/20 0.37
HPGD P15428 4/20 0.37
SCN9A Q15858 1/20 0.37
CRBN Q96SW2 1/20 0.36
FFAR1 O14842 5/20 0.36
HCRTR2 O43614 1/20 0.34
ABL1 P00519 1/20 0.33
NQO2 P16083 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767288 0.97 FAAH (0.40) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14766064 0.95 PPARD (0.37) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14767158 0.94 FAAH (0.39) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14765944 0.93 CRBN (0.38) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14767272 0.93 HPGD (0.37) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14767305 0.92 HPGD (0.39) PPARDHPGDFFAR1HCRTR2ABL1
SCHEMBL14766721 0.91 SCN9A (0.39) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14766978 0.91 FAAH (0.36) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14767247 0.90 FAAH (0.35) PPARDFAAHHPGDSCN9ACRBN
SCHEMBL14766744 0.90 CRBN (0.38) PPARDFAAHHPGDSCN9ACRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed