SCHEMBL14767288

SCHEMBL14767288

CCCCOc1ccc(OC(=O)C2CCC(c3ccc(C4CCC(OCCCC)CC4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 10/20 0.40
CRBN Q96SW2 1/20 0.39
SCN9A Q15858 1/20 0.38
PPARD Q03181 4/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 2/20 0.35
FFAR1 O14842 1/20 0.35
PPARG P37231 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767192 0.97 PPARD (0.38) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14767158 0.97 FAAH (0.39) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14765944 0.95 CRBN (0.38) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14766978 0.94 FAAH (0.36) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14767247 0.93 FAAH (0.35) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14766064 0.93 PPARD (0.37) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14766744 0.93 CRBN (0.38) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14766721 0.92 SCN9A (0.39) FAAHCRBNSCN9APPARDHPGD
SCHEMBL14767272 0.91 HPGD (0.37) FAAHCRBNSCN9APPARDHPGD
SCHEMBL12742191 0.90 FAAH (0.41) FAAHCRBNSCN9APPARDHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed