Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767149 | 0.97 | SCN9A (0.37) | SCN9AHPGDFAAHCRBNTHRA | |
| SCHEMBL14766721 | 0.94 | SCN9A (0.39) | SCN9AHPGDFAAHCRBNTHRA | |
| SCHEMBL14766978 | 0.93 | FAAH (0.36) | SCN9AHPGDFAAHCRBNALDH1A1 | |
| SCHEMBL14767307 | 0.92 | HPGD (0.34) | SCN9AHPGDHCRTR2ALDH1A1L3MBTL1 | |
| SCHEMBL14767272 | 0.91 | HPGD (0.37) | SCN9AHPGDFAAHCRBNHCRTR2 | |
| SCHEMBL14767131 | 0.91 | SCN9A (0.39) | SCN9AHPGDFAAHCRBNTHRA | |
| SCHEMBL14766346 | 0.91 | HPGD (0.35) | SCN9AHPGDTHRATHRBHCRTR2 | |
| SCHEMBL14767247 | 0.91 | FAAH (0.35) | SCN9AHPGDFAAHCRBNALDH1A1 | |
| SCHEMBL14766278 | 0.91 | CRBN (0.35) | SCN9AHPGDFAAHCRBNHCRTR2 | |
| SCHEMBL14767153 | 0.90 | HPGD (0.35) | SCN9AHPGDHCRTR2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |