Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766653 | 0.97 | THRA (0.41) | THRATHRBSCN9AALDH1A1HTT | |
| SCHEMBL14767301 | 0.94 | THRA (0.39) | THRATHRBSCN9AALDH1A1HTT | |
| SCHEMBL12741135 | 0.91 | THRA (0.41) | THRATHRBSCN9AALDH1A1HTT | |
| SCHEMBL14767022 | 0.91 | THRA (0.38) | THRATHRBSCN9AALDH1A1HTT | |
| SCHEMBL14766823 | 0.90 | SCN9A (0.38) | THRATHRBSCN9AALDH1A1HTT | |
| SCHEMBL14767210 | 0.89 | KCNQ3 (0.41) | THRATHRBKMT2APDE4DKCNQ3 | |
| SCHEMBL12741138 | 0.89 | THRA (0.45) | THRATHRBSCN9AALDH1A1HTT | |
| SCHEMBL14767068 | 0.88 | THRA (0.36) | THRATHRBSCN9AFAAHPPARD | |
| SCHEMBL12741149 | 0.88 | THRA (0.47) | THRATHRBSCN9AALDH1A1PLA2G2A | |
| SCHEMBL12741143 | 0.88 | THRA (0.47) | THRATHRBSCN9AALDH1A1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |