Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.35 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12741133 | 0.92 | KCNQ3 (0.41) | KCNQ3KCNQ2KMT2AKDM1ASERPINE1 | |
| SCHEMBL12719425 | 0.92 | KCNQ3 (0.41) | KCNQ3KCNQ2KMT2AKDM1ASERPINE1 | |
| SCHEMBL14767301 | 0.91 | THRA (0.39) | KCNQ3KCNQ2KMT2AKDM1ASERPINE1 | |
| SCHEMBL12719228 | 0.91 | KCNQ3 (0.40) | KCNQ3KCNQ2KMT2AKDM1ASERPINE1 | |
| SCHEMBL14766783 | 0.90 | KDM4E (0.38) | KCNQ3KCNQ2KMT2ASERPINE1SMN1; SMN2 | |
| SCHEMBL14766653 | 0.90 | THRA (0.41) | KCNQ3KCNQ2KMT2ASMN1; SMN2THRA | |
| SCHEMBL12741132 | 0.90 | KCNQ3 (0.39) | KCNQ3KCNQ2KMT2AKDM1ASERPINE1 | |
| SCHEMBL14767249 | 0.89 | KMT2A (0.34) | KCNQ3KCNQ2KMT2ASERPINE1THRA | |
| SCHEMBL14767252 | 0.89 | THRA (0.41) | KCNQ3KCNQ2KMT2ASMN1; SMN2THRA | |
| SCHEMBL12741124 | 0.89 | KCNQ3 (0.41) | KCNQ3KCNQ2KMT2AKDM1ASERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |