Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767285 | 0.93 | MAPT (0.46) | MAPTKMT2AFFAR1THRBFFAR4 | |
| SCHEMBL14767114 | 0.93 | MAPT (0.47) | MAPTKMT2AFFAR1PPARDTHRB | |
| SCHEMBL12742721 | 0.93 | MAPT (0.43) | MAPTKMT2AFFAR1PPARDCCNC | |
| SCHEMBL12742738 | 0.93 | THRB (0.43) | MAPTKMT2AFFAR1PPARDTHRB | |
| SCHEMBL14767151 | 0.93 | KMT2A (0.45) | MAPTKMT2AFFAR1PPARDCCNC | |
| SCHEMBL12742736 | 0.92 | MAPT (0.42) | MAPTKMT2AFFAR1PPARDCCNC | |
| SCHEMBL14767138 | 0.92 | MAPT (0.48) | MAPTKMT2AFFAR1PPARDCCNC | |
| SCHEMBL14766610 | 0.91 | MAPT (0.48) | MAPTKMT2AFFAR1PPARDCCNC | |
| SCHEMBL14767221 | 0.91 | MAPT (0.43) | MAPTKMT2AFFAR1PPARDCCNC | |
| SCHEMBL12742723 | 0.90 | MAPT (0.50) | MAPTFFAR1PPARDTHRBFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |