Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766751 | 0.93 | FFAR1 (0.46) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL12741887 | 0.93 | ALDH1A1 (0.41) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL13586232 | 0.93 | MAPT (0.45) | KMT2AMAPTTHRBFFAR1PPARD | |
| SCHEMBL12741858 | 0.93 | MAPT (0.43) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL14767299 | 0.93 | MAPT (0.45) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL12741893 | 0.92 | MAPT (0.42) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL14767086 | 0.91 | MAPT (0.43) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL12741863 | 0.90 | MAPT (0.50) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL13586234 | 0.89 | PTGS2 (0.40) | KMT2AMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL12741868 | 0.89 | KCNQ3 (0.37) | KMT2AMAPTTHRBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |