SCHEMBL14767330

SCHEMBL14767330

CNc1ccc2cc3ccc(N(C)I)cc3nc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 9/20 0.52
APP P05067 1/20 0.52
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
MAPT P10636 1/20 0.44
TNNI3 P19429 1/20 0.44
TNNT2 P45379 1/20 0.44
RAB9A P51151 1/20 0.44
TNNC1 P63316 1/20 0.44
RUNX1 Q01196 1/20 0.44
CBFB Q13951 1/20 0.44
EGFR P00533 3/20 0.42
NOS1 P29475 1/20 0.35
APAF1 O14727 2/20 0.34
POLB P06746 1/20 0.34
PABPC1 P11940 1/20 0.34
MMP14 P50281 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12393176 0.86 TERT (0.71) TERTAPPMEN1KMT2ANPC1
SCHEMBL31340959 0.86 TERT (0.71) TERTAPPMEN1KMT2ANPC1
SCHEMBL3856587 0.84 MEN1 (0.57) TERTAPPMEN1KMT2ANPC1
SCHEMBL30435339 0.84 MEN1 (0.57) TERTAPPMEN1KMT2ANPC1
SCHEMBL17423262 0.75 GLA (0.58) TERTAPPMEN1KMT2ANPC1
SCHEMBL12854930 0.74 MEN1 (0.67) TERTAPPMEN1KMT2ANPC1
SCHEMBL14065475 0.74 MEN1 (0.47) TERTAPPMEN1KMT2ANPC1
Acridine Orange SCHEMBL297155 0.69 TERT (1.00) TERTAPPMEN1KMT2ANPC1
Acridine Orange SCHEMBL29361720 0.69 TERT (1.00) TERTAPPMEN1KMT2ANPC1
SCHEMBL24527560 0.68 MAPT (0.61) TERTMEN1KMT2ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2568288-A1 Means and methods for staining acid-fast cells Koninklijke Philips Electronics N.V. (NL) 2013-03-13 EP disclosed