SCHEMBL17423262

SCHEMBL17423262

CNc1ccc2cc3ccccc3nc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 4/20 0.58
MAPT P10636 3/20 0.58
ALDH1A1 P00352 3/20 0.58
HPGD P15428 3/20 0.58
ACHE P22303 1/20 0.58
HTR3A P46098 1/20 0.53
NCF1 P14598 1/20 0.52
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
NPC1 O15118 4/20 0.49
KDM4E B2RXH2 4/20 0.49
RAB9A P51151 3/20 0.49
TNNI3 P19429 1/20 0.49
TNNT2 P45379 1/20 0.49
TNNC1 P63316 1/20 0.49
RUNX1 Q01196 1/20 0.49
CBFB Q13951 1/20 0.49
PABPC1 P11940 2/20 0.47
POLB P06746 2/20 0.47
APAF1 O14727 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3856587 0.90 MEN1 (0.57) GLAMAPTALDH1A1HPGDACHE
SCHEMBL30435339 0.90 MEN1 (0.57) GLAMAPTALDH1A1HPGDACHE
Acridine SCHEMBL27854164 0.84 ALDH1A1 (0.62) GLAMAPTALDH1A1HPGDACHE
Acridine SCHEMBL29072530 0.81 ALDH1A1 (0.79) GLAMAPTALDH1A1HPGDACHE
SCHEMBL14065475 0.79 MEN1 (0.47) GLAMAPTALDH1A1HPGDACHE
SCHEMBL12854930 0.79 MEN1 (0.67) GLAMAPTALDH1A1ACHEHTR3A
SCHEMBL12393176 0.78 TERT (0.71) GLAMAPTKMT2AMEN1NPC1
SCHEMBL31340959 0.78 TERT (0.71) GLAMAPTKMT2AMEN1NPC1
SCHEMBL17918989 0.77 EGFR (0.55) GLAMAPTALDH1A1HPGDACHE
SCHEMBL6759670 0.77 ALDH1A1 (0.50) MAPTALDH1A1HPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016005979-A1 METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS IN HONEYBEES THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2016-01-14 WO disclosed