Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12440457 | 0.89 | MCHR1 (0.59) | ESR1ESR2 | |
| SCHEMBL14767389 | 0.84 | ESR1 (0.60) | ESR1ESR2 | |
| SCHEMBL14767387 | 0.84 | ESR1 (0.63) | ESR1ESR2 | |
| SCHEMBL12440442 | 0.78 | MCHR1 (0.65) | ESR1ESR2 | |
| SCHEMBL12439956 | 0.77 | LTA4H (0.64) | ESR1ESR2 | |
| SCHEMBL12441462 | 0.77 | MCHR1 (0.59) | ESR1ESR2 | |
| SCHEMBL8810978 | 0.74 | ESR1 (0.66) | ESR1ESR2 | |
| SCHEMBL8811463 | 0.74 | ESR1 (0.61) | ESR1ESR2 | |
| SCHEMBL12440740 | 0.73 | MCHR1 (0.61) | ESR1ESR2 | |
| SCHEMBL2475993 | 0.73 | ESR1 (0.75) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558578-B1 | NOVEL ALKYNE COMPOUNDS HAVING AN MCH ANTAGONISTIC EFFECT AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 2013-03-13 | — | — | EP | disclosed |