Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5420238 | 0.85 | FLT3 (0.52) | FYNCCNE1CDK2MKNK1 | |
| SCHEMBL14668773 | 0.82 | TTK (0.42) | FYNCCNE1CDK2MKNK1RIPK2 | |
| SCHEMBL12404462 | 0.81 | FYN (0.48) | FYNCCNE1CDK2MKNK1HSD17B1 | |
| SCHEMBL3466151 | 0.77 | TTK (0.62) | — | |
| SCHEMBL5399308 | 0.76 | FLT3 (0.48) | — | |
| SCHEMBL3467072 | 0.75 | PDE5A (0.59) | FYN | |
| SCHEMBL3466464 | 0.75 | TTK (0.48) | FYN | |
| SCHEMBL3471112 | 0.75 | FYN (0.47) | FYN | |
| SCHEMBL3469144 | 0.74 | TTK (0.61) | FYN | |
| SCHEMBL12409229 | 0.74 | TTK (0.51) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567960-A2 | Imidazo[1,2-a]pyrazine compounds for treatment of viral infections such as hepatitis | Biofocus DPI Limited (GB) | 2013-03-13 | — | — | EP | disclosed |