Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12323392 | 0.84 | MAPK1 (0.42) | MAPK1KDM4EADORA3CDC7ROCK2 | |
| SCHEMBL641559 | 0.78 | MAPK1 (0.46) | MAPK1KDM4EADORA3CDC7ROCK2 | |
| Hydrochloric Acid SCHEMBL643220 | 0.77 | MAPK1 (0.45) | MAPK1KDM4EADORA3CDC7ROCK2 | |
| SCHEMBL1622415 | 0.72 | MAPK1 (0.44) | MAPK1KDM4EADORA3CDC7ROCK2 | |
| SCHEMBL23607971 | 0.69 | NPC1 (0.33) | ADORA3GAAALDH1A1 | |
| SCHEMBL12102045 | 0.68 | MAPK1 (0.55) | MAPK1KDM4EADORA3CDC7ROCK2 | |
| SCHEMBL16428676 | 0.65 | MAPK1 (0.54) | MAPK1KDM4EADORA3PIM1GSK3B | |
| SCHEMBL14767736 | 0.65 | ADORA2A (0.46) | MAPK1KDM4EGAASMN1; SMN2LMNA | |
| SCHEMBL12322236 | 0.64 | QPCT (0.38) | MAPK1CDC7GAKQPCT | |
| SCHEMBL12322232 | 0.62 | MAPK1 (0.31) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |