Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1622894 | 0.77 | ABCB1 (0.62) | ADORA2AADORA1ABCB1LIMK1L3MBTL1 | |
| SCHEMBL18997462 | 0.74 | ADORA2A (0.48) | ADORA2AADORA1ABCB1LIMK1L3MBTL1 | |
| SCHEMBL6711629 | 0.71 | SMN1; SMN2 (0.62) | LIMK1L3MBTL1MAPK1GAAMAPT | |
| SCHEMBL1622072 | 0.66 | ABCB1 (0.62) | ADORA2AADORA1ABCB1LIMK1L3MBTL1 | |
| SCHEMBL6015570 | 0.66 | ABCB1 (0.57) | ADORA2AADORA1ABCB1LIMK1L3MBTL1 | |
| SCHEMBL14767743 | 0.65 | MAPK1 (0.42) | ADORA2AMAPK1GAAMAPTKDM4E | |
| SCHEMBL23852245 | 0.63 | TLR8 (0.36) | ADORA2AADORA1GAAMAPTKDM4E | |
| SCHEMBL6015528 | 0.63 | ABCB1 (0.59) | ADORA2AADORA1ABCB1LIMK1L3MBTL1 | |
| SCHEMBL6015560 | 0.63 | ABCB1 (0.59) | ADORA2AADORA1ABCB1LIMK1L3MBTL1 | |
| SCHEMBL13757221 | 0.62 | MAPK1 (0.47) | ABCB1LIMK1L3MBTL1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573559-A1 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |